My I-140 was approved after RFE. submited 08/25/2005, RFE notice 09/08/2005, RFE response received by USCIS on 11/15/2005, approved 11/17/2005. I sent in 6 independent letters and highlighted extensive media reports of my work (quote my boss's name and colleagues) , important citations, and many download times of my paper. prepared by a lawyer.
Get a lot of useful information from this forum, especially from WorthIt and fas2000. if you want to know the detail about my RFE, search under my id "newniw"
Don't worry if you get RFE, just try your best.
Good luck to all.