摘要如下：
“Our results indicate a fast up-take of BNT162b2 into human liver cell line Huh7, leading to changes in LINE-1 expression and distribution. We also show that BNT162b2 mRNA is reverse transcribed intracellularly into DNA in as fast as 6 h upon BNT162b2 exposure.”
“In the BNT162b2 toxicity report, no genotoxicity nor carcinogenicity studies have been provided [26]. Our study shows that BNT162b2 can be reverse transcribed to DNA in liver cell line Huh7, and this may give rise to the concern if BNT162b2-derived DNA may be integrated into the host genome and affect the integrity of genomic DNA, which may potentially mediate genotoxic side effects. At this stage, we do not know if DNA reverse transcribed from BNT162b2 is integrated into the cell genome. Further studies are needed to demonstrate the effect of BNT162b2 on genomic integrity, including whole genome sequencing of cells exposed to BNT162b2, as well as tissues from human subjects who received BNT162b2 vaccination.”
我的理解是，该研究发现体外细胞逆转录发生的生化指标证据，但还不确信体内逆转录是否发生，需要做全基因组测序才能确定。
我的评点：如果最终被基因测序证明逆转录，基因毒性就被证明，那么被改变的基因就可能会被遗传。。。我因粗通毒理学原理，对MRNA 疫苗的基因毒性 一直有担心，所有一直强烈反对对小孩打这种疫苗，现在看来大概率我是对的。
原文请看：
https://www.mdpi.com/1467-3045/44/3/73/htm