My Eb1a was denied last year because CIS office thought it weak, please compare your qualifications with mine, hopefully you get some idea out of it:
1: 20 papers, 10 first authored ones, impact factor from 4-10
2: A national award
3. MD China, PhD, USA top 30 school
4. Journal reviwer: review articles from about 10 journals including PNAS
5. Two professional membership (both of them not very strict)
6. Citations: over 200
7. Recommendation letters: 8, big guys in my field from 6 countries
Rejected, Then I applied both OR and NIW
However, luck plays a critical role in the process. Don't be frightened if you have similar background with me