High number of Omicron mutations render antibodies ineffective - study
 

https://www.jpost.com/health-and-wellness/coronavirus/article-694237
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The research team found an unprecedented number of mutations in the Omicron S-protein. They analyzed the available sequences of the virus along with the structural data on the spike protein in order to understand the possible impact that the high number of mutations could have on the binding of antibodies to the virus.

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