Glad to got the message from USCIS that My NIW 485 was approved today. It takes me almost 2 years from ting to this final step. My understanding is: be patient. Every dog has his day. I learned a lot from this forum. Special thanks to Xiaobaitu and other warm-hearted expert who helped me before.
The basic information about my case:
working in the field of biology
NIW 140 + 485 filed on 09/2005 to VSC
Case transferred to NSC 05/2006;
I40 RFE in 09/2006;
140 approved 02/2007;
485 approved today without RFE, no update recently until today's approval notice
Lots of friends here are in the same boat, So, Be patient! It will be your turn soon!